Menopause 731 uses clinically studied extract of Siberian rhubarb (Rheum rhaponticum L.) root to address hot flashes, night sweats, irritability, mood swings, sleep disturbances, exhaustion, joint and muscle discomfort, vaginal dryness, urinary health, and hormone function associated with menopause. It’s comprehensive menopause relief in a convenient, once-daily tablet. Menopause 731 contains R. rhaponticum extract standardized for two unique compounds: rhaponticin and desoxyrhaponticin. In pre-clinical studies, this unique extract selectively activated a specific estrogen receptor, ER β, while leaving the ER α receptor alone. Scientists believe this is why Menopause 731 relieves widespread menopausal discomfort. Clinically evaluated in over 400 women The standardized extract in our Menopause 731 formula has been studied in randomized, placebo-controlled clinical trials ranging from 12 weeks to two years. Results were measured by standardized research questionnaires designed to evaluate menopausal discomforts; as well as a specialized survey that rates patients’ mood and emotional health. The research found that R. rhaponticum extracts produced: Up to 83% reduction in total menopausal discomforts7 Up to 83% reduction in hot flashes6 Up to 66% reduction in irritability and mood swings5 Hot flashes, irritability, mood swings, and more This extract produced significant relief for 11 distinct menopause discomforts, especially for women experiencing hot flashes, night sweats, irritability, and mood swings. Remarkably, study participants reported improvement in all of their discomforts, including sleep disturbances, exhaustion, joint and muscle discomforts, and vaginal dryness, as well as urinary and hormone health. Dosage and Use Take one (1) tablet daily, or as recommended by a healthcare practitioner. Caution Consult with your healthcare practitioner if you have, or have a history of, estrogen-dependent tumors. Warnings KEEP OUT OF REACH OF CHILDREN DO NOT EXCEED RECOMMENDED DOSE Do not purchase if the outer seal is broken or damaged. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.