5-lipoxygenase (5-LOX) is an enzyme that transforms fatty acids into leukotrienes. Since 5-LOX levels increase over time, excess 5-LOX has been linked to some of the common effects of normal aging.
Boswellia extract inhibits 5-LOX
The Indian plant Boswellia serrata contains compounds shown to inhibit 5-LOX to support joint and arterial health. Boswellia inhibits 5-LOX at the cellular level. Scientific data reveals that a compound in boswellia called AKBA (3-O-acetyl-11-keto-ß-boswellic acid) is the key to this beneficial action.
But boswellia compounds are poorly absorbed into the blood. For this reason, we’ve used ApresFlex, a standardized form of boswellia extract. ApresFlex absorbs into the blood 52% more than previously available boswellia extracts.
Dietary factors increase 5-LOX prevalence
The typical American diet adds to 5-LOX levels. Foods rich in omega-6 fatty acids like red meat, poultry, eggs and dairy products, along with high-glycemic carbohydrates, trigger production of arachidonic acid. The body produces 5-LOX enzyme in response to arachidonic acid.
Benefits of modulating 5-LOX
5-LOX creates compounds like leukotriene B4 out of arachidonic acid. Inhibiting leukotriene B4 helps support joint, arterial and tissue health.5 Inhibiting 5-LOX also helped support healthy cell division in preclinical models.
Each 100 mg vegetarian capsule of 5-LOX Inhibitor with ApresFlex is standardized to provide 20% of active AKBA from boswellia. Most people need only one capsule a day
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Dosage and Use
To inhibit the 5-lipoxygenase enzyme, take one (1) capsule daily, or as recommended by a healthcare practitioner.