Life Extension Optimized Folate (L-Methylfolate) (1000 mcg) -- 100 Vegetarian Capsules
- Optimized Folate benefits cardio health and nervous system function.
- Correct folate levels are vital to maintain proper homocysteine levels in your body.
- Chronic use of therapeutic aspirin and antacids can prevent your body from metabolizing folate.
- 5-MTHF is the most biologically available form of folate you can buy.
Life Extension Optimized Folate Can Help Those Who Have Problems Metabolizing Folate
Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. By helping to rid your body of excess homocysteine, Life Extension Optimized Folate benefits cardiovascular health and nervous system function.
Ensuring your body has the correct level of folate is vital for healthy cell division and protein synthesis. This is also essential for the maintenance of a healthy gastrointestinal tract. An increased need for folate occurs in certain conditions in which increased cell multiplication is necessary. Excessive use of certain medications like aspirin in therapeutic doses and antacids can prevent your body from properly metabolizing folate.
Individuals that are taking an ordinary folate supplements, may not be experiencing the full effect. This is due to that once ingested, not everyone converts folate to its biologically active form known as 5-methyltetrahydrofolate (5-MTHF). Research shows that many individuals have a genetic enzyme deficiency which prevents their body form converting folate to 5-MTHF. This condition leaves many individuals susceptible to lower blood folate levels (and higher than desired homocysteine levels).
One way you can combat this problem is to take the bioactive folate 5-MTHF directly. Bioactive folate 5-MTHF has been declassified as a drug and is now available as a dietary supplement. 5-MTHF has been shown to drastically increase red blood cell folate concentration, an indicator of folate status compared with folic acid supplementation. This bioactive form of folate is up to seven times more bioavailable than ordinary folic acid. This greater bioavailability is especially important in people who have a genetic enzyme deficiency since it requires no conversion to become metabolically active.
Individuals with higher than normal homocysteine levels have a higher risk of cognitive decline. Unlike folic acid, 5-MTHF is able to cross the blood-brain barrier, which is especially important for people with cognitive difficulties to enhance the synthesis of acetylcholine in the brain — the neurotransmitter associated with memory.
Studies have also found that the effectiveness of 5-MTHF can be taken one step farther by by co-supplementing with methylcobalamin (the active form of vitamin B12), vitamin B6, and riboflavin.
|Ingredients||Amount Per Serving|
|Folate [as (6S)-5-Methyltetrahydrofolic acid, glucosamine salt]^||1000 mcg|